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Antibody Product Overview
| ELK.No | ES4297 |
| Product name | IGFBP1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | IGFBP1; IBP1; Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; Placental protein 12; PP12 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3484 |
| Human Swiss-Prot | P08833 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IGFBP1 |
| Fields | |
| Gene name | IGFBP1 |
| Protein name | Insulin-like growth factor-binding protein 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 16006 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P47876 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25685 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P21743 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human IGFBP1. AA range:91-140 |
| Specificity | IGFBP1 Polyclonal Antibody detects endogenous levels of IGFBP1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 28kD |
| Background | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008], |
| Function | function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.,PTM:Phosphorylated; probably by casein kinase II. Alters the affinity of the protein for IGFs.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 thyroglobulin type-1 domain.,subunit:Binds equally well IGF1 and IGF2., |
| Subcellular location | Secreted. |
| Expression | Amniotic fluid,Decidua,Liver,Placenta,Skin, |
Additional Images
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Western Blot analysis of MCF7 cells using IGFBP1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
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: AO-06-ES4297-50
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