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Antibody Product Overview
| ELK.No | ES4373 |
| Product name | GDF-3 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | GDF3; Growth/differentiation factor 3; GDF-3 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9573 |
| Human Swiss-Prot | Q9NR23 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GDF-3 |
| Fields | >>Cytokine-cytokine receptor interaction |
| Gene name | GDF3 |
| Protein name | Growth/differentiation factor 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14562 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q07104 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360 |
| Specificity | GDF-3 Polyclonal Antibody detects endogenous levels of GDF-3 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 41kD |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016], |
| Function | online information:GDF3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked., |
| Subcellular location | Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. . |
| Expression | Kidney, |
Additional Images
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Western Blot analysis of L929 cells using GDF-3 Polyclonal Antibody. Antibody was diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Western Blot analysis of L929 cells using GDF-3 Polyclonal Antibody diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Western Blot analysis of K562 KB using GDF-3 Polyclonal Antibody diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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: AO-06-ES4373-100
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