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Bcl-2 (phospho Ser70) rabbit pAb
AO-06-ES4387-100
Antibody Product Overview
| ELK.No | ES4387 |
| Product name | Bcl-2 (phospho Ser70) rabbit pAb |
| Reactivity | Mouse;Rat |
| Applications | WB;ELISA |
| Other name | BCL2; Apoptosis regulator Bcl-2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | |
| Human Swiss-Prot | |
| Source | Rabbit |
| Isotype | IgG |
| Target | Bcl-2 |
| Fields | |
| Gene name | BCL2 |
| Protein name | Apoptosis regulator Bcl-2 |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | 12043 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | 24224 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P49950 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BCL2 around the phosphorylation site of Ser70. AA range:36-85 |
| Specificity | Phospho-Bcl-2 (S70) Polyclonal Antibody detects endogenous levels of Bcl-2 protein only when phosphorylated at S70. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 26kD |
| Background | BCL2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. |
| Function | |
| Subcellular location | |
| Expression |
Additional Images
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Western Blot analysis of JK cells using Phospho-Bcl-2 (S70) Polyclonal Antibody
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Western Blot analysis of Jurkat cells using Phospho-Bcl-2 (S70) Polyclonal Antibody
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Western blot analysis of BCL2 (Phospho-Ser70) Antibody. The lane on the right is blocked with the BCL2 (Phospho-Ser70) peptide.
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: AO-06-ES4387-100
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