GPR75 rabbit pAb

GPR75 rabbit pAb

AO-06-ES4573-100

GPR75 rabbit pAb 100μL

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€429.00
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Antibody Product Overview

ELK.NoES4573
Product nameGPR75 rabbit pAb
ReactivityHuman;Mouse
ApplicationsWB;IF;ELISA
Other nameGPR75; Probable G-protein coupled receptor 75
Size100μL
Unit price ($)248
Human gene ID10936
Human Swiss-ProtO95800
SourceRabbit
IsotypeIgG
TargetGPR75
Fields
Gene nameGPR75
Protein nameProbable G-protein coupled receptor 75
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID237716
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ6X632
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenThe antiserum was produced against synthesized peptide derived from human GPR75. AA range:381-430
SpecificityGPR75 Polyclonal Antibody detects endogenous levels of GPR75 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWestern Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)59kD
BackgroundGPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002],
Functionfunction:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer.,
Subcellular locationCell membrane; Multi-pass membrane protein .
ExpressionExpressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer. Also expressed by islet cells (at protein level).

Additional Images

Image 1
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Western Blot analysis of HT-29 cells using GPR75 Polyclonal Antibody
Image 2
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Immunofluorescence analysis of LOVO cells, using GPR75 Antibody. The picture on the right is blocked with the synthesized peptide.
Image 3
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Western blot analysis of lysates from HT-29 and K562 cells, using GPR75 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES4573-100
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Hurry! only 10 items left in stock.

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