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Antibody Product Overview
| ELK.No | ES4951 |
| Product name | DHHC-15 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | ZDHHC15; Palmitoyltransferase ZDHHC15; Zinc finger DHHC domain-containing protein 15; DHHC-15 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 158866 |
| Human Swiss-Prot | Q96MV8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DHHC-15 |
| Fields | |
| Gene name | ZDHHC15 |
| Protein name | Palmitoyltransferase ZDHHC15 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8BGJ0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZDHHC15. AA range:288-337 |
| Specificity | DHHC-15 Polyclonal Antibody detects endogenous levels of DHHC-15 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009], |
| Function | catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,disease:Defects in ZDHHC15 are the cause of mental retardation X-linked type 91 (MRX91) [MIM:300577]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.,domain:The DHHC domain is required for palmitoyltransferase activity.,function:Palmitoyltransferase specific for GAP43 and DLG4/PSD95.,PTM:Autopalmitoylated.,similarity:Belongs to the DHHC palmitoyltransferase family.,similarity:Contains 1 DHHC-type zinc finger.,tissue specificity:Expressed in placenta, liver, lung, kidney, heart and brain., |
| Subcellular location | Golgi apparatus membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic density . |
| Expression | Expressed in placenta, liver, lung, kidney, heart and brain. |
Additional Images
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Western Blot analysis of Jurkat cells using DHHC-15 Polyclonal Antibody
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: AO-06-ES4951-100
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