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EphA7 (phospho Tyr791) rabbit pAb
AO-06-ES5129-100
Antibody Product Overview
| ELK.No | ES5129 |
| Product name | EphA7 (phospho Tyr791) rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | EPHA7; EHK3; HEK11; Ephrin type-A receptor 7; EPH homology kinase 3; EHK-3; EPH-like kinase 11; EK11; hEK11 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2045 |
| Human Swiss-Prot | Q15375 |
| Source | Rabbit |
| Isotype | IgG |
| Target | EPHA7 |
| Fields | >>Axon guidance |
| Gene name | EPHA7 |
| Protein name | Ephrin type-A receptor 7 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 13841 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q61772 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 171287 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P54759 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human EphA7 (phospho Tyr791) |
| Specificity | Phospho-EphA7 (Y791) Polyclonal Antibody detects endogenous levels of EphA7 protein only when phosphorylated at Y791. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 112kD |
| Background | This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013], |
| Function | catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,subunit:Interacts with PRKCABP and GRIP1.,tissue specificity:Widely expressed., |
| Subcellular location | Cell membrane ; Single-pass type I membrane protein . |
| Expression | Widely expressed. |
Additional Images
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Western Blot analysis of JK cells using Phospho-EphA7 (Y791) Polyclonal Antibody
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: AO-06-ES5129-100
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