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Antibody Product Overview
| ELK.No | ES5444 |
| Product name | GALR1 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | IF;ELISA |
| Other name | GALR1; GALNR; GALNR1; Galanin receptor type 1; GAL1-R; GALR-1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 2587 |
| Human Swiss-Prot | P47211 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GALR1 |
| Fields | >>Neuroactive ligand-receptor interaction |
| Gene name | GALR1 |
| Protein name | Galanin receptor type 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14427 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P56479 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210 |
| Specificity | GALR1 Polyclonal Antibody detects endogenous levels of GALR1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 39kD |
| Observed band (KD) | |
| Background | The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008], |
| Function | function:Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,PTM:Palmitoylated on at least one of the three cysteine residues present in the C-terminal part.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
| Expression | Brain,Melanoma,Small intestine, |
Additional Images
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Immunofluorescence analysis of LOVO cells, using GALR1 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES5444-50
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