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Antibody Product Overview
| ELK.No | ES5552 |
| Product name | Contactin 6 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | CNTN6; Contactin-6; Neural recognition molecule NB-3; hNB-3 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 27255 |
| Human Swiss-Prot | Q9UQ52 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Contactin 6 |
| Fields | |
| Gene name | CNTN6 |
| Protein name | Contactin-6 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 53870 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JMB8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CNTN6. AA range:331-380 |
| Specificity | Contactin 6 Polyclonal Antibody detects endogenous levels of Contactin 6 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 114kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014], |
| Function | function:Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.,similarity:Belongs to the immunoglobulin superfamily. Contactin family.,similarity:Contains 4 fibronectin type-III domains.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord., |
| Subcellular location | Cell membrane ; Lipid-anchor, GPI-anchor . |
| Expression | Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord. |
Additional Images
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Western blot analysis of CNTN6 Antibody. The lane on the right is blocked with the CNTN6 peptide.
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Western blot analysis of the lysates from HeLa cells using CNTN6 antibody.
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: AO-06-ES5552-100
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