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Antibody Product Overview
| ELK.No | ES5569 |
| Product name | Gγ 5 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | IF;ELISA |
| Other name | GNG5; GNGT5; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 2787 |
| Human Swiss-Prot | P63218 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Gγ 5 |
| Fields | >>Ras signaling pathway;>>Chemokine signaling pathway;>>PI3K-Akt signaling pathway;>>Apelin signaling pathway;>>Circadian entrainment;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Cholinergic synapse;>>Serotonergic synapse;>>GABAergic synapse;>>Dopaminergic synapse;>>Relaxin signaling pathway;>>Morphine addiction;>>Alcoholism;>>Human cytomegalovirus infection;>>Kaposi sarcoma-associated herpesvirus infection;>>Human immunodeficiency virus 1 infection;>>Pathways in cancer |
| Gene name | GNG5 |
| Protein name | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q80SZ7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 1.0036e+008 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P63219 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GNG5. AA range:10-59 |
| Specificity | Gγ 5 Polyclonal Antibody detects endogenous levels of Gγ 5 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 7kD |
| Observed band (KD) | |
| Background | G protein subunit gamma 5(GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010], |
| Function | function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the G protein gamma family.,subunit:G proteins are composed of 3 units, alpha, beta and gamma., |
| Subcellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side . |
| Expression | Brain,Platelet,Umbilical cord blood, |
Additional Images
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Immunofluorescence analysis of A549 cells, using GNG5 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES5569-50
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