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Antibody Product Overview
| ELK.No | ES5575 |
| Product name | AQP11 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | AQP11; AQPX1; PSEC0027; Aquaporin-11; AQP-11 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 282679 |
| Human Swiss-Prot | Q8NBQ7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AQP11 |
| Fields | |
| Gene name | AQP11 |
| Protein name | Aquaporin-11 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 66333 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BHH1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 286758 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q8CHM1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from AQP11 . at AA range: 130-210 |
| Specificity | AQP11 Polyclonal Antibody detects endogenous levels of AQP11 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 26kD |
| Background | domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.,tissue specificity:Expressed at low levels in roots and leaves., |
| Function | domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.,tissue specificity:Expressed at low levels in roots and leaves., |
| Subcellular location | Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein . Cytoplasm . Cytoplasm, perinuclear region . Localizes mainly to the periphery of lipid droplets (PubMed:24845055). it accumulates partly in mitochondrial-associated endoplasmic reticulum membranes (PubMed:31546170). . |
| Expression | Detected in the sperm head and tail (at protein level) (PubMed:28042826). Expressed in subcutaneous adipocytes (PubMed:24845055). Expressed in testis, kidney and ejaculated spermatozoa (PubMed:19812234). |
Additional Images
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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES5575-50
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