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Antibody Product Overview
| ELK.No | ES5593 |
| Product name | GPR18 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | GPR18; GPCRW; N-arachidonyl glycine receptor; NAGly receptor; G-protein coupled receptor 18 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2841 |
| Human Swiss-Prot | Q14330 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GPR18 |
| Fields | |
| Gene name | GPR18 |
| Protein name | N-arachidonyl glycine receptor |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 110168 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8K1Z6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 679957 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | A1A5S3 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GPR18. AA range:191-240 |
| Specificity | GPR18 Polyclonal Antibody detects endogenous levels of GPR18 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 34kD |
| Background | function:Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells., |
| Function | function:Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . |
| Expression | Expressed in midpiece of spermatozoon (at protein level) (PubMed:27572937). Most abundant in testis and spleen (PubMed:16844083). Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells (PubMed:16844083). |
Additional Images
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Immunofluorescence analysis of HUVEC cells, using GPR18 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from 293 and Jurkat cells, using GPR18 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HUVECcells using GPR18 antibody.
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Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES5593-100
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