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Antibody Product Overview
| ELK.No | ES5750 |
| Product name | eIF4E3 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | EIF4E3; Eukaryotic translation initiation factor 4E type 3; eIF-4E type 3; eIF-4E3; eIF4E type 3; eIF4E-3 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 317649 |
| Human Swiss-Prot | Q8N5X7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | eIF4E3 |
| Fields | |
| Gene name | EIF4E3 |
| Protein name | Eukaryotic translation initiation factor 4E type 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 66892 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9DBB5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human EIF4E3. AA range:141-190 |
| Specificity | eIF4E3 Polyclonal Antibody detects endogenous levels of eIF4E3 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 24kD |
| Background | EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008], |
| Function | function:Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity.,similarity:Belongs to the eukaryotic initiation factor 4E family.,subunit:eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least eIF4A, eIF4E and eIF4G (By similarity). EIF4E3 interacts with EIF4G1, but not with EIF4EBP1, EIF4EBP2 and EIF4EBP3., |
| Subcellular location | cytoplasm,cytosol,mRNA cap binding complex, |
| Expression | Brain, |
Additional Images
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Western Blot analysis of 3T3 cells using eIF4E3 Polyclonal Antibody diluted at 1:1000
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Western blot analysis of lysates from LOVO cells, using EIF4E3 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HepG2 cells using EIF4E3 antibody.
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: AO-06-ES5750-100
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