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Antibody Product Overview
| ELK.No | ES5763 |
| Product name | HoxB2 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | HOXB2; HOX2H; Homeobox protein Hox-B2; Homeobox protein Hox-2.8; Homeobox protein Hox-2H; K8 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 3212 |
| Human Swiss-Prot | P14652 |
| Source | Rabbit |
| Isotype | IgG |
| Target | HoxB2 |
| Fields | |
| Gene name | HOXB2 |
| Protein name | Homeobox protein Hox-B2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P0C1T1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HOXB2. AA range:41-90 |
| Specificity | HoxB2 Polyclonal Antibody detects endogenous levels of HoxB2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer. [provided by RefSeq, Jul 2008], |
| Function | developmental stage:Expressed in whole embryos and fetuses at 5-9 weeks from conception.,function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Antp homeobox family. Proboscipedia subfamily.,similarity:Contains 1 homeobox DNA-binding domain., |
| Subcellular location | Nucleus. |
| Expression | Leukemia,Placenta, |
Additional Images
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Western blot analysis of lysates from MCF-7, HUVEC, A549, and LOVO cells, using HOXB2 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HUVECcells using HOXB2 antibody.
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: AO-06-ES5763-100
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