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Antibody Product Overview
| ELK.No | ES5822 |
| Product name | Synaptotagmin X rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC |
| Other name | SYT10; Synaptotagmin-10; Synaptotagmin X; SytX |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 341359 |
| Human Swiss-Prot | Q6XYQ8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Synaptotagmin X |
| Fields | |
| Gene name | SYT10 |
| Protein name | Synaptotagmin-10 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 54526 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9R0N4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 60567 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | O08625 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from Synaptotagmin X . at AA range: 380-460 |
| Specificity | Synaptotagmin X Polyclonal Antibody detects endogenous levels of Synaptotagmin X protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 55kD |
| Background | cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney., |
| Function | cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney., |
| Subcellular location | Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. . |
| Expression | Expressed only in pancreas, lung and kidney. |
Additional Images
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Western Blot analysis of 293 cells using Synaptotagmin X Polyclonal Antibody
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Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES5822-50
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