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Antibody Product Overview
| ELK.No | ES5840 |
| Product name | Septin 14 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC |
| Other name | SEPT14; Septin-14 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 346288 |
| Human Swiss-Prot | Q6ZU15 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Septin 14 |
| Fields | |
| Gene name | SEPT14 |
| Protein name | Septin-14 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9DA97 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SEPT14. AA range:341-390 |
| Specificity | Septin 14 Polyclonal Antibody detects endogenous levels of Septin 14 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 50kD |
| Background | SEPT14 is a member of the highly conserved septin family of GTP-binding cytoskeletal proteins implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis, and other cellular functions (Peterson et al., 2007 [PubMed 17922164]).[supplied by OMIM, Jul 2008], |
| Function | function:Involved in cytokinesis .,similarity:Belongs to the septin family., |
| Subcellular location | Cytoplasm . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Perikaryon . Cytoplasm, perinuclear region . Cytoplasmic vesicle, secretory vesicle, acrosome . Colocalizes with actin stress fibers (PubMed:17922164). Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (By similarity). . |
| Expression | Testis-specific (at protein level). |
Additional Images
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Western Blot analysis of 3T3 cells using Septin 14 Polyclonal Antibody
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Western blot analysis of SEPT14 Antibody. The lane on the right is blocked with the SEPT14 peptide.
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Western blot analysis of the lysates from Jurkat cells using SEPT14 antibody.
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Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES5840-50
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