Connexin 31.3 rabbit pAb

Connexin 31.3 rabbit pAb

AO-06-ES5859-100

Connexin 31.3 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES5859
Product nameConnexin 31.3 rabbit pAb
ReactivityHuman;Rat;Mouse;
ApplicationsWB;ELISA
Other nameGJC3; GJE1; Gap junction gamma-3 protein; Connexin-30.2; Cx30.2; Connexin-31.3; Cx31.3; Gap junction epsilon-1 protein
Size100μL
Unit price ($)248
Human gene ID349149
Human Swiss-ProtQ8NFK1
SourceRabbit
IsotypeIgG
TargetConnexin 31.3
Fields
Gene nameGJC3
Protein nameGap junction gamma-3 protein
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtQ921C1
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenThe antiserum was produced against synthesized peptide derived from human GJC3. AA range:151-200
SpecificityConnexin 31.3 Polyclonal Antibody detects endogenous levels of Connexin 31.3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)28kD
BackgroundThis gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010],
Functionfunction:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Gamma-type subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038 expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.,
Subcellular locationCell membrane ; Multi-pass membrane protein . Cell junction, gap junction .
ExpressionCNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.

Additional Images

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Western blot analysis of the lysates from K562 cells using GJC3 antibody.
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: AO-06-ES5859-100
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Hurry! only 10 items left in stock.

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