Français
English
Antibody Product Overview
| ELK.No | ES5888 |
| Product name | AQP1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | AQP1; CHIP28; Aquaporin-1; AQP-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 358 |
| Human Swiss-Prot | P29972 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AQP1 |
| Fields | >>Renin secretion;>>Proximal tubule bicarbonate reclamation;>>Bile secretion |
| Gene name | AQP1 |
| Protein name | Aquaporin-1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 11826 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q02013 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25240 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P29975 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AQP1. AA range:101-150 |
| Specificity | AQP1 Polyclonal Antibody detects endogenous levels of AQP1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 29kD |
| Background | This gene encodes a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imbalance in ocular fluid movement. [provided by RefSeq, Aug 2016], |
| Function | domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.,miscellaneous:Pharmacologically inhibited by submillimolar concentrations of mercury.,online information:Blood group antigen gene mutation database,online information:Liquid states - Issue 36 of July 2003,polymorphism:AQP1 is responsible for the Colton blood group system. Approximately 92% of Caucasians are Co(A+B-) (Ala-46), approximately 8% are Co(A+B+), and only 0.2% are Co(A-B+) (Val-46). Co(A-B-) which is very rare, is due to a complete absence of AQP1.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) fa |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver. |
Additional Images
No image
Western blot analysis of lysates from rat brain cells, using AQP1 Antibody. The lane on the right is blocked with the synthesized peptide.
No image
No image
No image
: AO-06-ES5888-100
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package