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Antibody Product Overview
| ELK.No | ES6000 |
| Product name | KCNF1 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA;IHC |
| Other name | KCNF1; Potassium voltage-gated channel subfamily F member 1; Voltage-gated potassium channel subunit Kv5.1; kH1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3754 |
| Human Swiss-Prot | Q9H3M0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | KCNF1 |
| Fields | |
| Gene name | KCNF1 |
| Protein name | Potassium voltage-gated channel subfamily F member 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 382571 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q7TSH7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KCNF1. AA range:191-240 |
| Specificity | KCNF1 Polyclonal Antibody detects endogenous levels of KCNF1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 55kD |
| Background | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008], |
| Function | domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.,function:Putative voltage-gated potassium channel.,similarity:Belongs to the potassium channel family. F subfamily.,subunit:Heteromultimer with KCNG3, KCNG4 and KCNV2. Interacts with DLG1.,tissue specificity:Detected in heart, brain, liver, skeletal muscle, kidney and pancreas., |
| Subcellular location | Membrane; Multi-pass membrane protein. |
| Expression | Detected in heart, brain, liver, skeletal muscle, kidney and pancreas. |
Additional Images
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Western blot analysis of KCNF1 Antibody. The lane on the right is blocked with the KCNF1 peptide.
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES6000-50
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