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Antibody Product Overview
| ELK.No | ES6256 |
| Product name | Mash2 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | ASCL2; BHLHA45; HASH2; Achaete-scute homolog 2; ASH-2; hASH2; Class A basic helix-loop-helix protein 45; bHLHa45; Mash2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 430 |
| Human Swiss-Prot | Q99929 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Mash2 |
| Fields | |
| Gene name | ASCL2 |
| Protein name | Achaete-scute homolog 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 17173 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O35885 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 24209 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P19360 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from Mash2 . at AA range: 1-80 |
| Specificity | Mash2 Polyclonal Antibody detects endogenous levels of Mash2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 25kD |
| Background | achaete-scute family bHLH transcription factor 2(ASCL2) Homo sapiens This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008], |
| Function | function:AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Expressed specifically in the extravillous trophoblasts of the developing placenta., |
| Subcellular location | Nucleus . |
| Expression | Expressed specifically in the extravillous trophoblasts of the developing placenta. |
Additional Images
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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES6256-100
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