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Antibody Product Overview
| ELK.No | ES6295 |
| Product name | MxB rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC |
| Other name | MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 4600 |
| Human Swiss-Prot | P20592 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MxB |
| Fields | >>Viral life cycle - HIV-1;>>Hepatitis C;>>Measles;>>Influenza A;>>Human papillomavirus infection;>>Coronavirus disease - COVID-19 |
| Gene name | MX2 |
| Protein name | Interferon-induced GTP-binding protein Mx2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9WVP9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from the Internal region of human MxB. |
| Specificity | MxB Polyclonal Antibody detects endogenous levels of MxB protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 82kD |
| Background | The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008], |
| Function | induction:By interferons.,similarity:Belongs to the dynamin family.,similarity:Contains 1 GED domain., |
| Subcellular location | Cytoplasm . Nucleus . Nucleus, nuclear pore complex . Localization to nuclear pores requires GTP-binding. |
| Expression | Brain, |
Additional Images
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Western Blot analysis of 293 cells using MxB Polyclonal Antibody
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES6295-100
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