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Antibody Product Overview
| ELK.No | ES6313 |
| Product name | MYL6 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC |
| Other name | MYL6; Myosin light polypeptide 6; 17 kDa myosin light chain; LC17; Myosin light chain 3; MLC-3; Myosin light chain alkali 3; Myosin light chain A3; Smooth muscle and nonmuscle myosin light chain alkali 6 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4637 |
| Human Swiss-Prot | P60660 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MYL6 |
| Fields | >>Vascular smooth muscle contraction;>>Tight junction;>>Oxytocin signaling pathway |
| Gene name | MYL6 |
| Protein name | Myosin light polypeptide 6 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 17904 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q60605 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 362816 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q64119 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from the Internal region of human MYL6. |
| Specificity | MYL6 Polyclonal Antibody detects endogenous levels of MYL6 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 17kD |
| Background | Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008], |
| Function | function:Regulatory light chain of myosin. Does not bind calcium.,similarity:Contains 3 EF-hand domains.,subunit:Myosin is an hexamer of 2 heavy chains and 4 light chains., |
| Subcellular location | cytosol,brush border,membrane,myosin complex,unconventional myosin complex,extracellular matrix,vesicle,extracellular exosome, |
| Expression | B-cell lymphoma,Brain,Duodenum,Eye,Lung,Placenta, |
Additional Images
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Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES6313-50
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