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Antibody Product Overview
| ELK.No | ES6394 |
| Product name | Nkx-6.1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | NKX6-1; NKX6A; Homeobox protein Nkx-6.1; Homeobox protein NK-6 homolog A |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 4825 |
| Human Swiss-Prot | P78426 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Nkx-6.1 |
| Fields | >>Maturity onset diabetes of the young |
| Gene name | NKX6-1 |
| Protein name | Homeobox protein Nkx-6.1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18096 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q99MA9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 65193 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | O35762 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from Nkx-6.1 . at AA range: 180-260 |
| Specificity | Nkx-6.1 Polyclonal Antibody detects endogenous levels of Nkx-6.1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 38kD |
| Observed band (KD) | |
| Background | In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008], |
| Function | function:May be important for control of islet development and/or regulation of insulin biosynthesis.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Pancreatic beta cells., |
| Subcellular location | Nucleus . |
| Expression | Pancreatic beta cells. |
Additional Images
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Western blot analysis of NKX61 Antibody. The lane on the right is blocked with the NKX61 peptide.
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: AO-06-ES6394-100
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