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Antibody Product Overview
| ELK.No | ES6493 |
| Product name | MRP-S18C rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IHC;IF;ELISA |
| Other name | MRPS18C; CGI-134; 28S ribosomal protein S18c; mitochondrial; MRP-S18-c; Mrps18-c; S18mt-c; 28S ribosomal protein S18-1, mitochondrial; MRP-S18-1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 51023 |
| Human Swiss-Prot | Q9Y3D5 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MRP-S18C |
| Fields | >>Ribosome |
| Gene name | MRPS18C |
| Protein name | 28S ribosomal protein S18c mitochondrial |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 68735 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8R2L5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MRPS18C. AA range:71-120 |
| Specificity | MRP-S18C Polyclonal Antibody detects endogenous levels of MRP-S18C protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 16kD |
| Background | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondria |
| Function | similarity:Belongs to the ribosomal protein S18P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins., |
| Subcellular location | Mitochondrion . |
| Expression | Brain, |
Additional Images
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Immunofluorescence analysis of MCF7 cells, using MRPS18C Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using MRPS18C Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from K562 cells, using MRPS18C Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HepG2 cells using MRPS18C antibody.
: AO-06-ES6493-100
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