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Antibody Product Overview
| ELK.No | ES6924 |
| Product name | BAI-2 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | IHC;IF;ELISA |
| Other name | BAI2; Brain-specific angiogenesis inhibitor 2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 576 |
| Human Swiss-Prot | O60241 |
| Source | Rabbit |
| Isotype | IgG |
| Target | BAI-2 |
| Fields | |
| Gene name | BAI2 |
| Protein name | Brain-specific angiogenesis inhibitor 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 230775 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8CGM1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BAI2. AA range:91-140 |
| Specificity | BAI-2 Polyclonal Antibody detects endogenous levels of BAI-2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 171kD |
| Observed band (KD) | |
| Background | This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014], |
| Function | function:Might be involved in angiogenesis inhibition.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 4 TSP type-1 domains.,subunit:Interacts with GABPB2.,tissue specificity:Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines. |
Additional Images
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Immunofluorescence analysis of HUVEC cells, using BAI2 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using BAI2 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES6924-50
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