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Antibody Product Overview
| ELK.No | ES7137 |
| Product name | Syndecan-4 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | SDC4; Syndecan-4; SYND4; Amphiglycan; Ryudocan core protein |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 6385 |
| Human Swiss-Prot | P31431 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Syndecan-4 |
| Fields | >>ECM-receptor interaction;>>Cell adhesion molecules;>>Proteoglycans in cancer;>>Fluid shear stress and atherosclerosis |
| Gene name | SDC4 |
| Protein name | Syndecan-4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20971 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O35988 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 24771 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P34901 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Syndecan4. AA range:145-194 |
| Specificity | Syndecan-4 Polyclonal Antibody detects endogenous levels of Syndecan-4 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 22kD |
| Background | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008], |
| Function | function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Homodimer. Interacts with CDCP1, with GIPC PDZ domain and with NUDT16L1/SDOS (By similarity). Interacts with SDCBP.,tissue specificity:Expressed in epithelial and fibroblastic cells., |
| Subcellular location | [Isoform 1]: Membrane ; Single-pass type I membrane protein . Secreted . Shedding of the ectodomain produces a soluble form. .; [Isoform 2]: Secreted. |
| Expression | Expressed in epithelial and fibroblastic cells. |
Additional Images
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Western Blot analysis of HepG2 cells using Syndecan-4 Polyclonal Antibody
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Immunofluorescence analysis of HeLa cells, using Syndecan4 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Syndecan4 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from HepG2 cells, using Syndecan4 Antibody. The lane on the right is blocked with the synthesized peptide.
: AO-06-ES7137-50
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