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Antibody Product Overview
| ELK.No | ES7143 |
| Product name | p53AIP1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | IHC;IF;ELISA |
| Other name | TP53AIP1; p53-regulated apoptosis-inducing protein 1; p53AIP1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 63970 |
| Human Swiss-Prot | Q9HCN2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | p53AIP1 |
| Fields | >>p53 signaling pathway;>>Apoptosis |
| Gene name | TP53AIP1 |
| Protein name | p53-regulated apoptosis-inducing protein 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TPIP1. AA range:75-124 |
| Specificity | p53AIP1 Polyclonal Antibody detects endogenous levels of p53AIP1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 13kD |
| Observed band (KD) | |
| Background | This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011], |
| Function | function:May play an important role in mediating p53/TP53-dependent apoptosis.,induction:By p53/TP53.,tissue specificity:Only found to be expressed in thymus., |
| Subcellular location | Mitochondrion . |
| Expression | Only found to be expressed in thymus. |
Additional Images
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Immunofluorescence analysis of A549 cells, using TPIP1 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human thymus gland tissue, using TPIP1 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES7143-50
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