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Antibody Product Overview
| ELK.No | ES7204 |
| Product name | Ran BP-17 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IHC |
| Other name | RANBP17; Ran-binding protein 17 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 64901 |
| Human Swiss-Prot | Q9H2T7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Ran BP-17 |
| Fields | >>Nucleocytoplasmic transport |
| Gene name | RANBP17 |
| Protein name | Ran-binding protein 17 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 66011 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q99NF8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RANBP17. AA range:145-194 |
| Specificity | Ran BP-17 Polyclonal Antibody detects endogenous levels of Ran BP-17 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 125kD |
| Background | RAN binding protein 17(RANBP17) Homo sapiens The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002], |
| Function | function:May function as a nuclear transport receptor.,similarity:Belongs to the exportin family.,subunit:Binds to nucleoporins and the GTP-bound form of Ran.,tissue specificity:Highly expressed in testis, moderately in pancreas and weakly in other tissues studied., |
| Subcellular location | Cytoplasm . Nucleus . Nucleus, nuclear pore complex . |
| Expression | Highly expressed in testis, moderately in pancreas and weakly in other tissues studied. |
Additional Images
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Western blot analysis of RANBP17 Antibody. The lane on the right is blocked with the RANBP17 peptide.
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Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES7204-50
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