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Antibody Product Overview
| ELK.No | ES7766 |
| Product name | NT5C1A rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IF;ELISA |
| Other name | NT5C1A; Cytosolic 5'-nucleotidase 1A; cN1A; Cytosolic 5'-nucleotidase IA; cN-I; cN-IA |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 84618 |
| Human Swiss-Prot | Q9BXI3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NT5C1A |
| Fields | >>Purine metabolism;>>Pyrimidine metabolism;>>Nicotinate and nicotinamide metabolism;>>Metabolic pathways;>>Nucleotide metabolism |
| Gene name | NT5C1A |
| Protein name | Cytosolic 5'-nucleotidase 1A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 230718 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | A3KFX0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NT5C1A. AA range:151-200 |
| Specificity | NT5C1A Polyclonal Antibody detects endogenous levels of NT5C1A protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 41kD |
| Background | Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008], |
| Function | catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.,similarity:Belongs to the 5'-nucleotidase type 3 family.,tissue specificity:Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas., |
| Subcellular location | Cytoplasm. |
| Expression | Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas. |
Additional Images
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Immunofluorescence analysis of A549 cells, using NT5C1A Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from MCF-7 and HepG2 cells, using NT5C1A Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES7766-50
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