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Antibody Product Overview
| ELK.No | ES7774 |
| Product name | NHE-7 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | SLC9A7; NHE7; Sodium/hydrogen exchanger 7; Na(+)/H(+) exchanger 7; NHE-7; Solute carrier family 9 member 7 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 84679 |
| Human Swiss-Prot | Q96T83 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NHE-7 |
| Fields | >>Cardiac muscle contraction |
| Gene name | SLC9A7 |
| Protein name | Sodium/hydrogen exchanger 7 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 236727 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BLV3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SLC9A7. AA range:531-580 |
| Specificity | NHE-7 Polyclonal Antibody detects endogenous levels of NHE-7 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 80kD |
| Background | This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012], |
| Function | function:Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis.,miscellaneous:Is not inhibited by amiloride but by benzamil and quinine.,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,subunit:Interacts with SCAMP1, SCAMP2 and SCAMP5; may participate in its shuttling from trans-Golgi network to recycling endosomes.,tissue specificity:Ubiquitously expressed., |
| Subcellular location | Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . |
| Expression | Ubiquitously expressed. |
Additional Images
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Western blot analysis of lysates from Jurkat and COLO cells, using SLC9A7 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES7774-50
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