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Antibody Product Overview
| ELK.No | ES7921 |
| Product name | TALK-2 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | KCNK17; TALK2; TASK4; Potassium channel subfamily K member 17; 2P domain potassium channel Talk-2; Acid-sensitive potassium channel protein TASK-4; TWIK-related acid-sensitive K(+) channel 4; TWIK-related alkaline pH-activated K(+) channel |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 89822 |
| Human Swiss-Prot | Q96T54 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TALK-2 |
| Fields | |
| Gene name | KCNK17 |
| Protein name | Potassium channel subfamily K member 17 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KCNK17. AA range:271-320 |
| Specificity | TALK-2 Polyclonal Antibody detects endogenous levels of TALK-2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 37-42kD |
| Background | potassium two pore domain channel subfamily K member 17(KCNK17) Homo sapiens The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008], |
| Function | function:Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.,miscellaneous:Inhibited by Ba(2+), quinidine, chloroform and halothane. Activated at alkaline pH. Activated by quinine and isoflurane.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer ., |
| Subcellular location | Membrane; Multi-pass membrane protein. |
| Expression | Adrenal gland,Lung,Pancreas,Spleen, |
Additional Images
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Western blot analysis of lysates from Jurkat cells, using KCNK17 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES7921-100
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