Français
English
Antibody Product Overview
| ELK.No | ES7945 |
| Product name | StARD13 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA;IHC |
| Other name | STARD13; DLC2; GT650; StAR-related lipid transfer protein 13; 46H23.2; Deleted in liver cancer 2 protein; DLC-2; Rho GTPase-activating protein; START domain-containing protein 13; StARD13 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 90627 |
| Human Swiss-Prot | Q9Y3M8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | StARD13 |
| Fields | |
| Gene name | STARD13 |
| Protein name | StAR-related lipid transfer protein 13 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 243362 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q923Q2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human STA13. AA range:101-150 |
| Specificity | StARD13 Polyclonal Antibody detects endogenous levels of StARD13 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 125kD |
| Background | This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011], |
| Function | function:GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 1 START domain.,subunit:Homodimer. Interacts with TAX1BP1.,tissue specificity:Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines., |
| Subcellular location | Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet. |
| Expression | Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines. |
Additional Images
No image
Western blot analysis of STA13 Antibody. The lane on the right is blocked with the STA13 peptide.
No image
Immunofluorescence analysis of A549 cells, using STA13 Antibody. The picture on the right is blocked with the synthesized peptide.
No image
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
No image
: AO-06-ES7945-50
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package