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Antibody Product Overview
| ELK.No | ES8014 |
| Product name | SFRS11 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA;IHC |
| Other name | SRSF11; SFRS11; Serine/arginine-rich splicing factor 11; Arginine-rich 54 kDa nuclear protein; p54; Splicing factor; arginine/serine-rich 11 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9295 |
| Human Swiss-Prot | Q05519 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SFRS11 |
| Fields | |
| Gene name | SRSF11 |
| Protein name | Serine/arginine-rich splicing factor 11 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SFRS11. AA range:211-260 |
| Specificity | SFRS11 Polyclonal Antibody detects endogenous levels of SFRS11 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 54kD |
| Background | This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010], |
| Function | function:May function in pre-mRNA splicing.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Colocalizes with spliceosome components.,subunit:Interacts with PUF60., |
| Subcellular location | Nucleus. Colocalizes with spliceosome components. |
| Expression | Colon endothel,Epithelium,Fetal brain,Hepatoma,Human fetal |
Additional Images
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Western blot analysis of lysates from LOVO and RAW264.7 cells, using SFRS11 Antibody. The lane on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES8014-100
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