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Antibody Product Overview
| ELK.No | ES8049 |
| Product name | FXR2 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IHC;IF;ELISA |
| Other name | FXR2; FMR1L2; Fragile X mental retardation syndrome-related protein 2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9513 |
| Human Swiss-Prot | P51116 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FXR2 |
| Fields | |
| Gene name | FXR2 |
| Protein name | Fragile X mental retardation syndrome-related protein 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9WVR4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FXR2. AA range:551-600 |
| Specificity | FXR2 Polyclonal Antibody detects endogenous levels of FXR2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 74kD |
| Background | The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. [provided by RefSeq, Jul 2008], |
| Function | function:RNA-binding protein.,similarity:Belongs to the FMR1 family.,similarity:Contains 2 KH domains.,subunit:Interacts with FMR1 and FXR1. Interacts with CYFIP2 but not with CYFIP1. Interacts with TDRD3., |
| Subcellular location | Cytoplasm. |
| Expression | Brain,Epithelium,Lymph,PNS,Skin, |
Additional Images
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Immunofluorescence analysis of A549 cells, using FXR2 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using FXR2 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from COLO205 cells, using FXR2 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES8049-100
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