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Antibody Product Overview
| ELK.No | ES8050 |
| Product name | SCAMP1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC |
| Other name | SCAMP1; SCAMP; Secretory carrier-associated membrane protein 1; Secretory carrier membrane protein 1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9522 |
| Human Swiss-Prot | O15126 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SCAMP1 |
| Fields | |
| Gene name | SCAMP1 |
| Protein name | Secretory carrier-associated membrane protein 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 107767 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8K021 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29521 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P56603 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SCAMP1. AA range:273-322 |
| Specificity | SCAMP1 Polyclonal Antibody detects endogenous levels of SCAMP1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 32kD |
| Background | This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014], |
| Function | function:Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.,similarity:Belongs to the SCAMP family.,subunit:Interacts with AP1GBP1 and ITSN1 (By similarity). Interacts with SLC9A7.,tissue specificity:Widely expressed, with highest expression in brain., |
| Subcellular location | Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein . |
| Expression | Widely expressed, with highest expression in brain. |
Additional Images
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Western blot analysis of lysates from NIH/3T3 cells, using SCAMP1 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HeLa cells using SCAMP1 antibody.
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Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES8050-100
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