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Antibody Product Overview
| ELK.No | ES8102 |
| Product name | p164-RhoGEF rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | IHC;IF;ELISA |
| Other name | ARHGEF17; KIAA0337; TEM4; Rho guanine nucleotide exchange factor 17; 164 kDa Rho-specific guanine-nucleotide exchange factor; p164-RhoGEF; p164RhoGEF; Tumor endothelial marker 4 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9828 |
| Human Swiss-Prot | Q96PE2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | p164-RhoGEF |
| Fields | |
| Gene name | ARHGEF17 |
| Protein name | Rho guanine nucleotide exchange factor 17 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 207212 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q80U35 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ARHGEF17. AA range:431-480 |
| Specificity | p164-RhoGEF Polyclonal Antibody detects endogenous levels of p164-RhoGEF protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 222kD |
| Observed band (KD) | |
| Background | function:Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases.,similarity:Contains 1 DH (DBL-homology) domain.,tissue specificity:Highly expressed in the heart., |
| Function | function:Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases.,similarity:Contains 1 DH (DBL-homology) domain.,tissue specificity:Highly expressed in the heart., |
| Subcellular location | cytosol, |
| Expression | Highly expressed in the heart. |
Additional Images
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Immunofluorescence analysis of HepG2 cells, using CARD6 Antibody diluted at 1:50. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-human heart. 1, Antibody was diluted at 1:200(4° overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min). The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES8102-100
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