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Antibody Product Overview
| ELK.No | ES8482 |
| Product name | GABARAP rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | GABA(A) receptor-associated protein-like 2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 11345 |
| Human Swiss-Prot | P60520 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GABARAP |
| Fields | >>FoxO signaling pathway;>>Autophagy - other;>>Mitophagy - animal;>>Autophagy - animal;>>NOD-like receptor signaling pathway;>>GABAergic synapse |
| Gene name | GABARAPL2 FLC3A GEF2 |
| Protein name | GABARAP |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 93739 |
| Mouse gene link | |
| Mouse Swiss-Prot | P60521 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P60522 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthetic Peptide of GABARAP AA range: 26-75 |
| Specificity | GABARAP Polyclonal Antibody detects endogenous levels of GABARAP |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 17kD |
| Background | function:Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MAP1 LC3 family.,subunit:Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity). Interacts with ULK1.,tissue specificity:Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine., |
| Function | function:Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MAP1 LC3 family.,subunit:Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity). Interacts with ULK1.,tissue specificity:Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine., |
| Subcellular location | Cytoplasmic vesicle, autophagosome . Endoplasmic reticulum membrane . Golgi apparatus . |
| Expression | Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine. |
Additional Images
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Western Blot analysis of various cells using Antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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: AO-06-ES8482-100
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