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Antibody Product Overview
| ELK.No | ES8933 |
| Product name | PLD4 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC |
| Other name | Phospholipase D4 (PLD 4) (EC 3.1.4.4) (Choline phosphatase 4) (Phosphatidylcholine-hydrolyzing phospholipase D4) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 122618 |
| Human Swiss-Prot | Q96BZ4 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PLD4 |
| Fields | >>Glycerophospholipid metabolism;>>Ether lipid metabolism;>>Metabolic pathways |
| Gene name | PLD4 C14orf175 UNQ2488/PRO5775 |
| Protein name | Phospholipase D4 (PLD 4) (EC 3.1.4.4) (Choline phosphatase 4) (Phosphatidylcholine-hydrolyzing phospholipase D4) |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 104759 |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8BG07 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human PLD4 Polyclonal |
| Specificity | This antibody detects endogenous levels of PLD4. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 55kD |
| Background | catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,similarity:Belongs to the phospholipase D family.,similarity:Contains 2 PLD phosphodiesterase domains., |
| Function | catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,similarity:Belongs to the phospholipase D family.,similarity:Contains 2 PLD phosphodiesterase domains., |
| Subcellular location | Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass type II membrane protein . Nucleus . Early endosome . Cytoplasmic vesicle, phagosome . Activation of microglia induces translocation of PLD4 from the nucleus to the phagosomes. . |
| Expression | B-cell,T-cell, |
Additional Images
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Western blot analysis of various lysate, antibody was diluted at 1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES8933-100
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