GPDA rabbit pAb

GPDA rabbit pAb

AO-06-ES9149-50

GPDA rabbit pAb 50μL

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€299.00
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Antibody Product Overview

ELK.NoES9149
Product nameGPDA rabbit pAb
ReactivityHuman;Mouse;Rat
ApplicationsWB;ELISA
Other name
Size50μL
Unit price ($)148
Human gene ID2819
Human Swiss-ProtP21695
SourceRabbit
IsotypeIgG
TargetGPDA
Fields>>Glycerophospholipid metabolism
Gene nameGPD1
Protein nameGlycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)
Human gene link
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtP13707
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-ProtO35077
Rat Swiss linkView Rat Swiss-Prot
ImmunogenSynthesized peptide derived from human protein . at AA range: 210-290
SpecificityGPDA Polyclonal Antibody detects endogenous levels of protein.
FormulationLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000 ELISA 1:5000-20000
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)38kD
BackgroundThis gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],
Functioncatalytic activity:sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH.,enzyme regulation:Inhibited by zinc ions and sulfate.,similarity:Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.,subunit:Homodimer.,
Subcellular locationCytoplasm .
ExpressionExpressed in liver (at protein level).

Additional Images

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Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9149-50
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Hurry! only 10 items left in stock.

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