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Antibody Product Overview
| ELK.No | ES9258 |
| Product name | HUS1B rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 135458 |
| Human Swiss-Prot | Q8NHY5 |
| Source | Rabbit |
| Isotype | IgG |
| Target | HUS1B |
| Fields | |
| Gene name | HUS1B |
| Protein name | Checkpoint protein HUS1B (hHUS1B) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8K572 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 160-240 |
| Specificity | HUS1B Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 30kD |
| Background | The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008], |
| Function | similarity:Belongs to the HUS1 family.,subunit:Interacts with RAD1 and RAD9B.,tissue specificity:Expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes., |
| Subcellular location | nucleolus,checkpoint clamp complex,site of double-strand break, |
| Expression | Expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes. |
Additional Images
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Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9258-50
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