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Antibody Product Overview
| ELK.No | ES9261 |
| Product name | IKBL1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4795 |
| Human Swiss-Prot | Q9UBC1 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IKBL1 |
| Fields | |
| Gene name | NFKBIL1 IKBL |
| Protein name | NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O88995 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | Q8R2H1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 70-150 |
| Specificity | IKBL1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 41kD |
| Background | This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009], |
| Function | disease:Mutations in the promoter region of NFKBIL1 represent the second rheumatoid arthritis susceptibility locus within the HLA region [MIM:180300].,function:May be a negative regulator of NF-kappa-B activation.,similarity:Contains 2 ANK repeats.,tissue specificity:Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes., |
| Subcellular location | Nucleus . Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus. |
| Expression | Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes. |
Additional Images
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Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9261-50
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