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Antibody Product Overview
| ELK.No | ES9402 |
| Product name | AQP8 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 343 |
| Human Swiss-Prot | O94778 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AQP8 |
| Fields | >>Bile secretion |
| Gene name | AQP8 |
| Protein name | Aquaporin-8 (AQP-8) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P56404 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P56405 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 70-150 |
| Specificity | AQP8 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 28kD |
| Background | Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. [provided by RefSeq, Jul 2008], |
| Function | domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Expressed only in pancreas and colon., |
| Subcellular location | Mitochondrion membrane ; Multi-pass membrane protein . |
| Expression | Detected in the sperm midpiece (at protein level) (PubMed:28042826). Expressed only in pancreas and colon. |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9402-100
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