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Antibody Product Overview
| ELK.No | ES9473 |
| Product name | CABP4 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 57010 |
| Human Swiss-Prot | P57796 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CABP4 |
| Fields | |
| Gene name | CABP4 |
| Protein name | Calcium-binding protein 4 (CaBP4) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8VHC5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CABP4 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 30kD |
| Background | This gene encodes a member of the CABP family of calcium binding protein characterized by four EF-hand motifs. Mutations in this gene are associated with congenital stationary night blindness type 2B. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014], |
| Function | disease:Defects in CABP4 are the cause of congenital stationary night blindness type 2B (CSNB2B) [MIM:610427]. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision.,function:May play a role in normal synaptic function, probably through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals. Modulator of CACNA1F, shifting the activation range to more hyperpolarized voltages.,similarity:Contains 4 EF-hand domains.,subcellular location:Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors.,subunit:Interacts with CACNA1F., |
| Subcellular location | Cytoplasm . Cell junction, synapse, presynapse . Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors. . |
| Expression | Expressed in retina and in the inner hair cells (IHC) of the cochlea. |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9473-50
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