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Antibody Product Overview
| ELK.No | ES9799 |
| Product name | PGRC1 rabbit pAb |
| Reactivity | Human;Rat;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10857 |
| Human Swiss-Prot | O00264 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PGRC1 |
| Fields | |
| Gene name | PGRMC1 HPR6.6 PGRMC |
| Protein name | Membrane-associated progesterone receptor component 1 (mPR) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O55022 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P70580 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 20-100 |
| Specificity | PGRC1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 21kD |
| Background | This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010], |
| Function | domain:The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 107 and 131.,function:Receptor for progesterone.,similarity:Belongs to the cytochrome b5 family. MAPR subfamily.,similarity:Contains 1 cytochrome b5 heme-binding domain.,tissue specificity:Widely expressed, with highest expression in liver and kidney., |
| Subcellular location | Microsome membrane ; Single-pass membrane protein . Smooth endoplasmic reticulum membrane ; Single-pass membrane protein . Mitochondrion outer membrane ; Single-pass membrane protein ; Extracellular side . |
| Expression | Widely expressed, with highest expression in liver and kidney. Expressed by endometrial glands and stroma (at protein level) (PubMed:23793472). |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9799-100
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