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Antibody Product Overview
| ELK.No | ES9811 |
| Product name | IMP2L rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 83943 |
| Human Swiss-Prot | Q96T52 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IMP2L |
| Fields | >>Protein export |
| Gene name | IMMP2L |
| Protein name | Mitochondrial inner membrane protease subunit 2 (EC 3.4.21.-) (IMP2-like protein) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8BPT6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Specificity | IMP2L Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 19kD |
| Background | This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011], |
| Function | disease:Defects in IMMP2L may be a cause of Gilles de la Tourette syndrome (GTS) [MIM:137580]. GTS is a neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities.,function:Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.,similarity:Belongs to the peptidase S26 family.,similarity:Belongs to the peptidase S26 family. IMP2 subfamily.,subunit:Heterodimer of 2 subunits, IMMPL1 and IMMPL2.,tissue specificity:Expressed in all tissues tested except adult liver and lung., |
| Subcellular location | Mitochondrion inner membrane ; Single-pass membrane protein . |
| Expression | Expressed in all tissues tested except adult liver and lung. |
Additional Images
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Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9811-50
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