NGDN rabbit pAb

NGDN rabbit pAb

AO-06-ES9910-50

NGDN rabbit pAb 50μL

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Antibody Product Overview

ELK.NoES9910
Product nameNGDN rabbit pAb
ReactivityHuman;Mouse
ApplicationsWB;ELISA
Other name
Size50μL
Unit price ($)148
Human gene ID25983
Human Swiss-ProtQ8NEJ9
SourceRabbit
IsotypeIgG
TargetNGDN
Fields
Gene nameNGDN C14orf120
Protein nameNeuroguidin (EIF4E-binding protein)
Human gene link
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtQ9DB96
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human protein . at AA range: 240-320
SpecificityNGDN Polyclonal Antibody detects endogenous levels of protein.
FormulationLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000 ELISA 1:5000-20000
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)34kD
BackgroundNeuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008],
Functionfunction:Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs.,similarity:Belongs to the SAS10 family.,subcellular location:Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites.,subunit:Interacts with CPEB1 and EIF4E.,
Subcellular locationNucleus . Nucleus, nucleolus . Chromosome, centromere . Cytoplasm . Cell projection, axon . Cell projection, dendrite . Cell projection, filopodium . Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity). Translocated from nucleolus to nuclear foci in response to UV damage. .
ExpressionBrain,Epithelium,Placenta,

Additional Images

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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9910-50
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Hurry! only 10 items left in stock.

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