Anti-RUNX1/AML1 Rabbit pAb - 50 µL

AO-03-GB11797-50
  • Specification: 50 µL
  • Applications: IHC | IF
  • Species: M,R | M,R
  • Dilution: 1: 200-1: 1000 | 1: 250-1: 500
  • Positive tissue: spleen, lymph gland, placenta | spleen, lymph gland, placenta
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Product InformationDescriptionRUNX1 rabbit polyclonalProtein full nameRunt-related transcription factor 1SynonymsRunx1, RUNX1, AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha

Product Information

Protein full name

Runt-related transcription factor 1

Synonyms

Runx1, RUNX1, AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha, runt related transcription factor 1

Uniprot ID

Q03347

Immunogen

Recombinant protein corresponding to Mouse Runt-related transcription factor 1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm(β subunit )

Applications

ApplicationsSpeciesDilutionPositive Tissue
IHC/IFMouse, Rat1: 200-1: 1000placenta, lymph, spleen

Background

Runt-related transcription factor 1 (RUNX1) is a transcription factor that regulates the differentiation of hematopoietic stem cells into mature blood cells. In addition it plays a major role in the development of the neurons that transmit pain. It belongs to the Runt-related transcription factor (RUNX) family of genes which are also called core binding factor-α (CBFα). RUNX proteins form a heterodimeric complex with CBFβwhich confers increased DNA binding and stability to the complex.

Images

01EN1OWzq2iJ0Mt.jpg

IHC analysis of RUNX1/AML1(GB11797).
Sample: Mouse placenta, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98°C, 20 min.
Primary antibody: 1: 250, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

02Pa3J7eBgO74dV.jpg

IHC analysis of RUNX1/AML1(GB11797).
Sample: Rat lymph, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98°C, 20 min.
Primary antibody: 1: 250, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

03cURXC2Z4Pc5bc.jpg

IHC analysis of RUNX1/AML1(GB11797).
Sample: Rat spleen, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98°C, 20 min.
Primary antibody: 1: 250, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

Storage

Storage Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 µg/mL BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

Datasheet: Download datasheet 1

: AO-03-GB11797-50
: 10 Items
Hurry! only 10 items left in stock.

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