Anti-GPNMB Rabbit pAb - 100 µL

Anti-GPNMB Rabbit pAb - 100 µL

Antibodies-Oncology
AO-03-GB111475-100
  • Specification: 100 µL
  • Applications: WB
  • Species: H,M,R
  • Dilution: 1:500-1:1000
  • Positive tissue: brain, liver, heart
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Product Information

Protein full name

Transmembrane glycoprotein NMB

Synonyms

DC-HIL, Dendritic cell-associated transmembrane protein, Osteoactivin, Gpnmb, Dchil, Hgfin, Nmb

Uniprot ID

Q99P91

Immunogen

Recombinant protein corresponding to Mouse GPNMB

Isotype

IgG

Predicted MW./Observed MW.

64 kDa / 64 kDa

Purity

Affinity purification

Applications

ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse, Rat1: 500-1: 1000brain, liver, heart

Background

GPNMB also known as HGFIN, osteoactivin, and DC-HIL, is a type I membrane glycoprotein involved in various biological processes, including inflammation, invasion and metastasis of malignant tumors, cell differentiation, and tissue regeneration. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB acts as an osteogenic factor that stimulates osteoblast differentiation in vivo and in vitro.

Images

013HN4IRpimhzWu.jpg

 WB analysis of GPNMB(GB111475).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

02Z24XC8nTSUL7L.jpg

 WB analysis of GPNMB(GB111475).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

Storage

Storage Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 µg/mL BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

Datasheet: Download datasheet 1

Antibodies-Oncology
: AO-03-GB111475-100
: 10 Items
Hurry! only 10 items left in stock.

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