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Antibody Product Overview
| ELK.No | EM1051 |
| Product name | CK19 Mouse mAb |
| Reactivity | Human, Rat, Mouse |
| Applications | IHC |
| Other name | Cytokeratin 19, K19, K1CS, keratin 19, KRT19 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 3880 |
| Human Swiss-Prot | P08727 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | IHC 1:200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 44kDa |
| Background | This protein is a member of the keratin family. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7. |
| Function | |
| Subcellular location | Cytoskeleton,Cytosol |
| Expression |
Additional Images
IHC staining of human colon cancer tissue with CK19 mouse mAb(11F5) diluted at 1:200.
: EM1051-100
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