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CA IX/Carbonic Anhydrase IX Mouse mAb
EM1076-100
Antibody Product Overview
| ELK.No | EM1076 |
| Product name | CA IX/Carbonic Anhydrase IX Mouse mAb |
| Reactivity | Human |
| Applications | WB, IHC, IP |
| Other name | CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, carbonic anhydrase IX, G250, Membrane antigen MN, MN, P54/58N, pMW1, RCC associated antigen G250 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 768 |
| Human Swiss-Prot | Q16790 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | WB 1:3,000 IP 1:200 IHC 1:100-200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 35-38kDa |
| Background | The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors. |
| Function | |
| Subcellular location | Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane. |
| Expression |
Additional Images
Western blot analysis of 1) Hela, 2) 293T, with CA IX Mouse mAb diluted at 1:5,000.
1、Input: Hela Cell Lysate 2、IP product: IP dilute 1:200 Western blot analysis: primary antibody : EM1076 1:2,000 Secondary antibody: Goat anti-Mouse IgG, Light chain specific(S003), 1:5,000
Immunohistochemical analysis of paraffin-embedded Human Lung Caricnoma using CA IX/Carbonic Anhydrase IX（EM1076）Mouse mAb diluted at 1:200.
: EM1076-100
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