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IDE/Insulin Degrading Enzyme Mouse mAb
EM1083-50
Antibody Product Overview
| ELK.No | EM1083 |
| Product name | IDE/Insulin Degrading Enzyme Mouse mAb |
| Reactivity | Human |
| Applications | WB, IHC |
| Other name | Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3416 |
| Human Swiss-Prot | P14735 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | WB 1:1,000 IHC 1:200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 118kDa |
| Background | Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently. |
| Function | |
| Subcellular location | Cell membrane, Cytoplasm, Membrane, Secreted |
| Expression |
Additional Images
Western blot analysis of 1) Hela, 2) HepG2,with IDE Mouse mAb diluted at 1:2,000.
Western blot analysis of Hela, HepG2,with IDE Mouse mAb diluted at 1:2,000.
: EM1083-50
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